OTC Heartburn Drugs for GERD The Best Antacids and More

There are many heartburn medications available for purchase to help ease the symptoms.

If none of these Indigestion remedies work, discuss with your physician regarding other options that might be helpful along with lifestyle adjustments.

Your doctor might want to examine if gastroesophageal respiratory disease or GERD is the reason for your symptoms.

Non-Prescription Medications That Cure Heartburn Comprise:

Antacids To Treat Heartburn

Antacids help neutralize the stomach acid and cut the risk of heartburn and acidic stomach acid, stomach indigestion, and stomach upset.

Certain antacids or Acid Reflux Medicine have simethicone which assists your body in getting rid of gas.

Certain antacids contain components that could cause diarrhoea, including magnesium, and constipation, including aluminium.

Some examples of antacids include:

  • Aluminium hydroxide gel
  • Calcium carbonate (Alka-Seltzer, Tums)
  • Magnesium Hydroxide (Milk of Magnesia)
  • Gaviscon, Gelusil, Maalox, Mylanta, Rolaids
  • Pepto-Bismol

It is recommended to take your antacids according to your doctor’s instructions or by the label; if you take tablets, chew the pills thoroughly before swallowing to ensure quick relief.

Follow the instructions on the label to ensure that you don’t get overdosed or misuse anti-inflammatory medications i.e., Aciloc 300 Mg.

The side effects can include constipation and diarrhoea, changing bowel movements’ colours, and abdominal discomfort.

  • Acid Reducers To Treat Heartburn

Two kinds of medications cut down on acid production within the stomach. The histamine antagonists and proton pump inhibitors (PPIs).

Some examples of blockers H2 readily available on the market include:

  • Cimetidine (Tagamet HB)
  • Famotidine (Pepcid AC), Zantac 360
  • Nizatidine

Notice that the H2 blocker ranitidine found in earlier Zantac items was taken off the shelves in 2020 after it was determined to be an agent that causes cancer.

Esomeprazole, a proton pump inhibitor (Nexium 24HR) and lansoprazole (Prevacid 24HR), and Omeprazole (Prilosec OTC) are sold over-the-counter for treating regular acid reflux (two plus times each weekly) up to 14 days. These medicines are also available as stronger prescriptions. Use them by the instructions on the label or as directed by your physician.

If these medicines don’t alleviate the symptoms or discomforts from heartburn becoming more severe or persist for more than two weeks, you must consult your physician.

Combination Antacid/Acid Reducer for Heartburn

Pepcid Complete combines the ability to neutralize the acid in an antacid with the acid-reducing properties of an H2 blocking drug. Zegerid OTC includes a proton-pump inhibitor with sodium bicarbonate.

Which is the best option to Treat Heartburn?

The majority of the over-the-counter medications can, in varying degrees they can, help relieve the effects of heartburn.

If you’re experiencing more severe symptoms of heartburn that aren’t being reduced by these medicines likeĀ Pan 40 Mg or have used these medications for longer than two weeks, consult your physician.

You might require more vital prescription medication and tests to determine what’s causing the symptoms.

Which OTC is the most effective in treating heartburn?

The intensity and severity of GERD symptoms will determine whether the OTC treatment is proper for you.

Antacids are usually the first choice treatment to treat mild heartburn. In neutralizing the acidity in your stomach, these medicines will help relieve heartburn symptoms immediately.

Blockers of H2 and PPIs lower the amount of stomach acid your body produces. They’re also more effective when you’re suffering from frequent heartburn.

The drugs can be more challenging to start, but they can stop heartburn for up to 24 hours.

In more severe or ongoing heartburn conditions, PPIs are generally more efficient than H2 blockers when treating GERD.

Combining OTC Products

Certain people might takeĀ Omez 20 Mg or a mixture of H2 blockers, antacids, and PPIs to control acid reflux and avoid repeat episodes.

However, they can result in side effects like constipation or diarrhoea in some instances.

Make sure you consult your physician before mixing the use of any OTC remedies for GERD with any other medication.

Acid Reducers For Heartburn

Other OTC medicines can help with GERD effects by reducing the volume of acid your stomach produces. More powerful versions of these medications are also available on prescription.

Blockers of H2

Blockers of H2 decrease the quantity of acid produced in your stomach and reduce the chance of heartburn. They typically begin to work within 1-3 hours from the time you take them. They work slower than antacids. However, they give relief for longer, from 8 to 12 hours.

H2 blockers can be purchased OTC and on prescription. These OTC H2 blockers are:

  • cimetidine (Tagamet HB)
  • Famotidine (Calmicid, Fluid, Pepcid AC)
  • nizatidine (Axid, Axid AR)

H2 blockers may cause adverse consequences, such as:

  • Headache
  • Constipation
  • Diarrhoea
  • Nausea
  • Vomiting

Proton-Pump Inhibitors (Ppis)

Proton Pump Inhibitors (PPIs) stop the production of stomach acid. They’re among the most effective medications for reducing acid production and are suitable for those who suffer from greater frequently experiencing heartburn.

PPIs are sold in pills. A majority are prescribed only, while some are also available over-the-counter:

PPIs can trigger a myriad of adverse reactions, such as:

  • Diarrhoea
  • Nausea
  • Vomiting
  • Discomfort In Your Abdomen
  • Stomach Upset
  • Headache

The risk of side effects is lower when taking PPIs than H2 blockers; however, they can be more severe. They can include an increased chance of developing pneumonia or bone fracture and, occasionally, hypomagnesemia(low magnesium levels) that could pose a life-threatening risk.

What Do I Have To Choose From My OTC Treatment Alternatives?

There are three kinds of OTC medicines to treat heartburn.


Antacids relieve heartburn (indigestion). They relieve heartburn by altering the stomach acid responsible for heartburn. The most common OTC anti-inflammatory drugs like Neksium 20 Mg include:

  • Mylanta
  • Rolaids
  • Tums

Histamine-2 (H2) Blockers

H2 blockers help relieve and prevent heartburn. They work to reduce the amount of acid that is produced by the stomach. They typically begin with about one to three hours. They offer acid suppression for some time. Because acid reducers could interact with other medications, consult your doctor or pharmacist before using them in conjunction with prescription drugs.

OTC PPIs treat frequent heartburn (which occurs every two or more every day). They aren’t designed for immediate relief from heartburn because they can require between one and four days before they are effective.

Contrarily, PPIs are prescribed to treat issues such as gastroesophageal resuscitation disease (GERD), a stomach condition, small intestine ulcers, and irritation of the oesophagus. PPIs help by reducing the quantity of acid created by the stomach.

Because acid reducers could be incompatible with other medications, consult your physician or pharmacist before use in the case of prescription drugs.

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